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How to Start a Supplement Brand: Manufacturer's Secrets to Formulation & Manufacturing

  • Writer: CLS
    CLS
  • Jul 15
  • 3 min read

Updated: Aug 4

The global nutrition supplement industry is projected to exceed $360 billion by 2030. This growth is driven by the rising demand for clean-label, plant-based, and performance-driven products. If you’ve ever thought about creating your own supplement brand, now is the perfect time to turn that dream into a profitable business.


However, success requires more than just a great idea. It demands a strategic plan backed by manufacturing expertise.


That’s where CLS Manufacturing comes in. As an expert US supplement contract manufacturer, we’ll guide you through the essential steps — from formulation and ingredient sourcing to compliance, branding, and product launch. Here are the 7 key steps to start a supplement brand.


pre-workout supplement
Pre-workout Supplement Brand

Define Your Niche & Product Concept


Before sourcing ingredients or choosing a label design, it’s crucial to define your brand's target niche. Ask yourself these questions to help pinpoint your direction:


  • Who is your target customer?

  • What pain point does your product solve?

  • What delivery method will they prefer — liquid or powder?


Popular supplement markets in 2025 include:


  • Women’s hormone balance

  • Gut and immune health

  • Nootropics and brain-boosting blends

  • Vegan collagen and plant-based proteins


We help brands translate ideas into viable formulas by offering market trend insights, proprietary delivery systems, and formulation strategy.


Partner with a Compliant Manufacturer


Choosing the right manufacturing partner is critical. Here are key factors to consider when selecting a US supplement contract manufacturer:


  • GMP-certified facilities for consistent quality

  • FDA compliance for labeling and formulation

  • In-house ingredient sourcing and testing

  • Support for custom and private label manufacturing


What we offer:


  • Clean-label sourcing with GMP-certified facilities

  • Organic, vegan, and allergen-free ingredient options

  • State-of-the-art R&D labs and packaging customization

  • Regulatory compliance guidance from Day 1


Let our experience guide your brand from raw ingredients to ready-for-market supplements.


Formulate & Source Ingredients with Expertise


We guide you through a seamless 5-step formulation process:


  1. Concept validation and health claim research

  2. Ingredient sourcing from verified global vendors

  3. Small-batch testing for taste, texture, and stability

  4. Lab validation for potency and safety

  5. Custom flavoring, encapsulation, and packaging


Whether you're creating a collagen booster or a stress-relief blend, our experts ensure your formula meets both industry trends and consumer expectations.


Regulatory Compliance & Legal Requirements


Launching a supplement brand means navigating compliance and legal requirements. Key areas include:


  • FDA regulations under DSHEA

  • Proper label formatting and structure-function claims

  • FTC advertising compliance

  • Local/state regulations, such as Utah’s UDAF plan reviews and food permits


Our regulatory team ensures your products meet all state and federal guidelines, giving you peace of mind before hitting the market.


Production Timeline & Startup Costs


Here’s what to expect during the initial startup phase of your supplement business journey:


Launching a nutrition supplement brand involves several key stages — from formulating your product to receiving your finished inventory, ready for market. While the process may seem overwhelming, we have a streamlined approach that keeps your brand on schedule and within scope.


Typical Production Timeline


Once your product concept and formula are finalized, the production timeline generally includes:


  • Sourcing and testing of ingredients

  • Custom formulation development and flavor profiling

  • Small-batch pilot runs for stability and efficacy

  • Packaging design and compliance checks

  • Full-scale manufacturing and final inspection


From formula approval to shelf-ready products, the average production window typically ranges from a few weeks to several months. This depends on complexity, packaging requirements, and ingredient sourcing logistics.


Startup Cost Considerations


Your total investment will depend on multiple factors, including:


  • Type of supplement (e.g., powder or liquid)

  • Packaging design (e.g., custom labeling, eco-friendly options)

  • Ingredient profile and availability

  • Batch size and frequency of reorders


We offer flexibility with low minimum order quantities (MOQs), allowing you to test your product in the market without large upfront inventory. Our scalable solutions ensure you can start lean and grow strong, maintaining healthy profit margins as your brand expands.


As your trusted manufacturing partner, we help you evaluate cost-efficient options for formulation, sourcing, production, and packaging—ensuring that your brand is built for both impact and sustainability.


Ready to Launch? Now You Know How to Start a Supplement Brand!


Launching a nutrition supplement brand isn’t just about having a great idea. It’s about bringing that idea to life with the right formulation, strategy, and manufacturing support.


Whether you’re starting small or aiming to build the next big supplement empire, let us help you start your next supplement brand and product line.


From formulation and ingredient sourcing to compliance and packaging, we’re your go-to partner every step of the way.


Let's chat about CLS Manufacturing and your next nutrition supplement brand. We are the right nutrition supplement manufacturing partner for you!


Get a free estimate/quote by contacting us today!



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